abstract：BACKGROUND AND OBJECTIVE:Left ventricular hypertrophy (LVH) is the most frequent manifestation of cardiac damage in hypertension. The objective of this study was to evaluate the prevalence of LVH in hypertensive patients of long evolution at Primary Care (PC) and to describe their epidemiological profile. PATIENTS AND...

journal_title：Medicina clinica

authors： Fernández Villaverde JM,Maestro Saavedra FJ,Allut Vidal G,Grigorian Shamagian L,Otero-Raviña F,González-Juanatey JR,Grupo Barbanza.

更新日期：2007-06-09 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aims of the GEMM Family Study are to clarify the genetic determinants of cardiovascular disease (CVD) risk in individuals born and living in Mexico. The authors evaluate the heritabilities (h2) of CVD risk factors in Mexicans from a preliminary cohort already studied. Heritabilities for CVD...

journal_title：Medicina clinica

authors： Bastarrachea RA,Kent J Jr,Comuzzie AG

更新日期：2007-06-02 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Since World Health Organization (WHO) recommends brief interventions for smoking cessation to be included systematically in daily practise as a part of clinical work, the main aim of this study is to know if this intervention is done by health professionals working in hospital wards in a genera...

journal_title：Medicina clinica

authors： Nieva G,Gual A,Mondon S,Walther M,Saltó E

更新日期：2007-05-19 00:00:00

abstract：BACKGROUND AND OBJECTIVE:After the good results obtained by the Société Française d'Oncologie Pédiatrique (SFOP) regarding the pediatric B-type non-Hodgkin's (Burkitt and large B-cell) lymphoma and L3 leukemia, the Sociedad Española de Hematología y Oncología Pediátricas (SHOP) decided to use the same treatment protoco...

journal_title：Medicina clinica

authors： Forns M,Javier G,Estella J,Fernández-Delgado R,Gallego S,García-Miguel P,Indiano JM,Navajas A,Pardo N,en representación del grupo SHOP de las Sociedades Españolas de Hematología (SEHP) y Oncología Pediátricas (SEOP).

更新日期：2007-05-05 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Sense of Coherence (SOC) is a construct relating to coping strategies in the face of traumatic events. SOC is defined as a personal disposition towards perceiving life experiences as understandable, manageable and meaningful. The construct has shown itself to be a predictor of self-reported and...

journal_title：Medicina clinica

authors： Virués-Ortega J,Martínez-Martín P,Del Barrio JL,Lozano LM,Grupo Español de Estudios Epidemiológicos sobre Envejecimiento.

更新日期：2007-04-07 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To assess the value of rituximab in systemic autoimmune diseases which are refractory to others treatments. PATIENTS AND METHOD:Prospective study on 12 patients -7 with systemic lupus erythematosus (SLE), 4 with Wegener's granulomatosis (WG), and 1 with overlapping connective disease and autoi...

journal_title：Medicina clinica

authors： García Hernández FJ,Ocaña Medina C,González León R,Garrido Rasco R,Colorado Bonilla R,Castillo Palma MJ,Sánchez Román J

更新日期：2007-03-31 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To evaluate the distribution of clinical, electrophysiological and biological variables, and their relationship with the CSF hypocretin-1 levels, in patients with central hypersomnias diagnosed as narcolepsy-cataplexy (NC), narcolepsy without cataplexy (NnC) and idiopathic hypersomnia (IH) base...

journal_title：Medicina clinica

authors： Martínez-Rodríguez JE,Iranzo A,Casamitjana R,Graus F,Santamaria J

更新日期：2007-03-17 00:00:00

abstract：:Heart failure (HF) is a cardiovascular disease with a permanent increase in prevalence, incidence and mortality. Current optimal therapies for HF are effective only for slowing, but not stopping, its progression. HF-related mortality is high, even at the time of the disease onset. Approximately 40% of HF-attributable ...

journal_title：Medicina clinica

authors： Formiga F,Manito N,Pujol R

更新日期：2007-02-24 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Clinical variability in myocardial infarction (MI) regarding age, comorbidities and atypical symptoms could determine gender differences in inhospital care. This study analyzes the magnitude and determinants of differences between men and women in early reperfusion therapy in people hospitalize...

journal_title：Medicina clinica

authors： Aldasoro E,Calvo M,Esnaola S,Hurtado de Saracho I,Alonso E,Audicana C,Arós F,Lekuona I,Arteagoitia JM,Basterretxea M,Marrugat J,IBERICA-País Vasco Group.

更新日期：2007-01-27 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The use of complementary and alternative medicine (CAM) is increasing in last years. Studies performed out of Spain have reported rates of CAM use of 40-50% among IBD patients. There are no available data on drug abuse among IBD patients. The aims of our study were to evaluate the rate and asso...

journal_title：Medicina clinica

authors： García-Planella E,Marín L,Domènech E,Bernal I,Mañosa M,Zabana Y,Gassull MA

更新日期：2007-01-20 00:00:00

abstract：:Several heritable disorders of glucose transport across cellular membranes have been recently characterized both genetically and pathophysiologically. Diseases such as glucose-galactose malabsorption, Fanconi-Bickel syndrome and GLUT1 deficiency syndrome are caused by mutation of transporters located in bowel, liver a...

journal_title：Medicina clinica

authors： Pascual JM

更新日期：2006-11-11 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Leptin is an hormone resulting from the obesity gene. Their actions could be important in the pathogenesis of the osteoporosis. The aim of this study is to analyse the influence of tobacco on serum leptin levels, and its relationship with bone mineral density (BMD) and steroid hormones. SUBJEC...

journal_title：Medicina clinica

authors： Supervía A,Enjuanes A,Vila J,Mellibovsky L,Nogués X,Díez-Pérez A

更新日期：2006-11-04 00:00:00

abstract：:Hypertension represents a relative risk of stroke up to 5 times. It is associated to ischaemic and haemorrhagic stroke. Hypertension produces an increase in brain vessels resistance and loss of the physiological mechanism of autoregulation, and it can be measured with transcranial doppler. Clinical trials have establi...

journal_title：Medicina clinica

authors： Serna Candel C,Moreno Pérez O,Moltó Jordà JM

更新日期：2006-10-28 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To estimate the prevalence of risk behaviors related to drug use and to identify factors associated with of accepting and passing on used syringes among intravenous drug users (IDU) recruited in Barcelona city and other surrounding areas in 2004. SUBJECTS AND METHOD:A cross-sectional study of ...

journal_title：Medicina clinica

authors： Folch C,Meroño M,Casabona J

更新日期：2006-10-14 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The plasma protein leakage produced in the bronchial mucose of patients with acute asthma might be associated to the quickness of the onset exacerbation. The aim of this study was to study this association. PATIENTS AND METHOD:22 patients with acute asthma were recruited, and the magnitude of ...

journal_title：Medicina clinica

authors： Bellido-Casado J,Plaza V,Belda J,Martínez-Brú C,Torrejón M,Sanchis J

更新日期：2006-09-30 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To study the effects of antenatal corticosteroids treatment to promote fetal lung maturation, on fetal growth, depending on the number of the courses administered. PATIENTS AND METHOD:The study was based on data from the Spanish Collaborative Study of Congenital Malformations (ECEMC), analysin...

journal_title：Medicina clinica

authors： Rodríguez-Pinilla E,Prieto-Merino D,Dequino G,Mejías C,Fernández P,Martínez-Frías ML,Grupo del ECEMC.

更新日期：2006-09-16 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Our goal was to know if the diagnosis of metabolic syndrome (MS) as defined by International Diabetes Federation (IDF) criteria 2005 identifies more subjects with atherogenic dyslipidemia and high cardiovascular risk than the National Cholesterol Education Program-Adult Treatment Panel III (NCE...

journal_title：Medicina clinica

authors： Real JT,Romero P,Martínez Hervas S,Pedro T,Carmena R,Ascaso JF

更新日期：2006-09-09 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aims of the present study were to analyze the prognosis after resuscitation from out-of-hospital sudden cardiac death in patients admitted to the coronary care unit, and to identify the predictor variables of morbi-mortality. PATIENTS AND METHOD:From November 1999 to January 2004 we analyz...

journal_title：Medicina clinica

authors： Vallès E,Martí V,Noguero M,Guindo J,Domínguez de Rozas JM

更新日期：2006-09-02 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To study the effect of clinical and demographic variables on mortality in patients with probable Alzheimer's disease treated with the cholinesterase inhibitor galantamine. PATIENTS AND METHOD:This retrospective cohort study reviewed 172 medical records, gathering information such as demographi...

journal_title：Medicina clinica

authors： López-Pousa S,Garre Olmo J,Vilalta Franch J,Turon Estrada A,Soler Cors O,Pericot Nierga I

更新日期：2006-07-08 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to investigate the presence of the most prevalent mutation in the SLC7A9 gene in families of the Mediterranean Spanish population and their association with clinical phenotypes. PATIENTS AND METHOD:Twenty cystinuria families were studied (6 type I, 12 non type I, and ...

journal_title：Medicina clinica

authors： Francés F,Portolés O,Corella D,Sorlí JV,Sabater A,Carrasco P,Guillén M

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To assess the relationship between reputation of hospitals, as determined by specialists' opinion, and their scientific production. MATERIAL AND METHOD:A questionnaire was sent to a sample of members of the Spanish Societies of Cardiology, Digestive Diseases, Neurology and Otorhinolaryngology....

journal_title：Medicina clinica

authors： Asenjo MA,Bertrán MJ,Guinovart C,Llach M,Prat A,Trilla A

更新日期：2006-05-27 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This article provides an epidemiological description of anesthesia practice in Catalonia, Spain, in 2003. PATIENTS AND METHOD:Descriptive data on sex, age, and physical status of patients according to American Society of Anesthesiologists (ASA) classification were taken from responses to the q...

journal_title：Medicina clinica

authors： Sabaté S,Canet J,Muñoz S,Castillo J,Lucas M,Mayoral V

更新日期：2006-05-24 00:00:00

abstract：:The ANESCAT 2003 survey has provided reliable information on all practices within the specialty of anesthesiology in a community comprising 6.7 million inhabitants (namely Catalonia, Spain). In a situation in which official statistics are lacking, the findings allow us to make predictions and plan the clinical and org...

journal_title：Medicina clinica

authors： Canet J,Gomar C,Castillo J,Villalonga A,Sabaté S,Hervàs C

更新日期：2006-05-24 00:00:00

abstract：:There are a great number of polymorphic genes in the human genome. Many of them codify enzymes that metabolizes drugs and xenobiotic agents, including carcinogens. Among the better known of them, there are a number of isozymes of the microsomal oxidative system (CYP3A4, CYP2C9, CYP2C19 y CYP2D6). This article reviews ...

journal_title：Medicina clinica

authors： Alonso-Navarro H,Jiménez-Jiménez FJ,García-Agúndez JA

更新日期：2006-05-13 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To assess the cessation and relapse rates of smoking, and analyze the associated variables in a 12-month follow-up study at a smoking cessation unit. SUBJECTS AND METHOD:Patients from the Area de Salud 19 of the Conselleria de Sanitat of the Generalitat Valenciana, coming to a smoking cessatio...

journal_title：Medicina clinica

authors： Pascual-Lledó JF,De la Cruz-Amorós E,Bustamante-Navarro R,Buades-Sánchez MR,Contreras-Santos C,Castillo-Aguilar C

更新日期：2006-04-29 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to describe an outbreak of Q fever in a group of people (day care centre for mental-handicapped individuals) previously exposed to animals in a school-farm. PATIENTS AND METHOD:A retrospective cohort study among the 25 mental-handicapped individuals and the 30 workers...

journal_title：Medicina clinica

authors： de los Ríos-Martín R,Sanz-Moreno JC,Martín-Martínez F,Tébar-Betegón MA,Cortés-García M,Escudero-Nieto R

更新日期：2006-04-22 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The ESEMeD-Spain project is an epidemiological study about mental disorders in Spain. We present 12 month-prevalence and lifetime-prevalence of the main mood, anxiety and alcohol use disorders; the influence of sociodemographic factors on its presence and age of onset of the disorders. SUBJECT...

journal_title：Medicina clinica

authors： Haro JM,Palacín C,Vilagut G,Martínez M,Bernal M,Luque I,Codony M,Dolz M,Alonso J,Grupo ESEMeD-España.

更新日期：2006-04-01 00:00:00

abstract：:Pulse pressure is calculated as the difference between the systolic and diastolic components of arterial blood pressure. Epidemiological studies have demonstrated that pulse pressure elevation directly correlates with cardiovascular mortality and morbidity, as well as with target organ damage. From a pathophysiologica...

journal_title：Medicina clinica

authors： de la Sierra A

更新日期：2006-03-18 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To describe an outbreak of Legionella pneumophila serogroup 1 in Mataró, Catalunya, Spain, in August 2002. The source of the microorganism was a cooling tower. PATIENTS AND METHOD:Prospective and observational study with analysis of epidemiological, clinical, and microbiological data. RESULTS...

journal_title：Medicina clinica

authors： Barrufet-Barqué MP,Sauca-Subias G,Force-Sanmartín L,Felip-Benach A,Martínez-Pérez E,Capdevila-Morell JA

更新日期：2006-02-11 00:00:00

abstract：:Nausea and vomiting are considered one of the most distressing side-effects of chemotherapy. Complete control of acute and delayed emesis improves quality of life and increases adherence to treatment. The frequency of nausea and vomiting depends primarily on the emetogenic potential of the chemotherapeutic agents used...

journal_title：Medicina clinica

authors： Gómez-Raposo C,Feliú-Batlle J,González-Baróna M

更新日期：2006-02-04 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To determine the incidence of adverse drug events (ADE) in hospitalized patients, identify those that were potentially preventable, and asses the drug classes involved, the clinical symptoms and the type of medication errors that led to the preventable ADE. PATIENTS AND METHOD:An observational...

journal_title：Medicina clinica

authors： Otero-López MJ,Alonso-Hernández P,Maderuelo-Fernández JA,Garrido-Corro B,Domínguez-Gil A,Sánchez-Rodríguez A

更新日期：2006-01-28 00:00:00

abstract：:The decision-making process includes a series of activities undertaken in biomedical journals from the moment a manuscript is received until it is accepted or rejected. Firstly, the manuscript is evaluated by the members of the Editorial Board, who analyze both its suitability for the journal and its scientific qualit...

journal_title：Medicina clinica

authors： Ribera JM,Cardellach F,Selva A,Editorial committee of Medicina Clínica.

更新日期：2005-12-01 00:00:00

abstract：:Clinical journals often publish economic evaluation studies of health technologies and programs. To improve the peer review process and, hence, the quality and validity of published studies, the British Medical Journal (BMJ) established publication guidelines for the publication of economic evaluations aimed at author...

journal_title：Medicina clinica

authors： Rovira-Forns J,Antoñanzas-Villar F

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Though there is a general agreement on the need of influenza vaccination (IV), very different results have been published about the magnitude of its effect. We evaluated the effectiveness of IV in the reduction of mortality in individuals over 65 years of age. PATIENTS AND METHOD:Prospective c...

journal_title：Medicina clinica

authors： Vila-Córcoles A,Ochoa-Gondar O,Ansa-Echeverría X,Gómez-Sorribes A,Espelt-Aluja P,Pascual-Morón I

更新日期：2005-11-19 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The standard treatment of the obstructive sleep apnea syndrome (OSAS) is the nCPAP. There is evidence that its use improves the quality of life of patients. The objective of the study is to measure the effect of nCPAP on the quality of life of patients in a Spanish cohort. PATIENTS AND METHOD:...

journal_title：Medicina clinica

authors： Mar J,Rivero-Arias O,Durán-Cantolla J,Alonso-Alvarez ML,Gaminde I,de la Torre-Muñecas G

更新日期：2005-11-05 00:00:00

abstract：:Pulmonary complications in HIV-infected patients are at present a first-rate problem. They are the main cause of hospital admission of these patients in our country. Most HIV-patients have a pulmonary complication during the evolution of the infection. The main etiologic diagnosis is bacterial pneumonia, especially pn...

journal_title：Medicina clinica

authors： Benito Hernández N,Moreno Camacho A,Gatell Artigas JM

更新日期：2005-10-22 00:00:00

abstract：:Celiac disease is manifested by an enteropathy caused by intolerance to gluten, a family of proteins found in wheat and other cereals. Following intestinal T-cell activation in predisposed individuals, different inflammatory mechanisms are triggered under the control of the cytokine balance including those with a pro-...

journal_title：Medicina clinica

authors： León AJ,Garrote JA,Arranz E

更新日期：2005-10-15 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Patients identified as risk drinkers usually fill a questionnaire in order to assess their alcohol dependence. In our setting, the Münchner Alkoholismus Test (MALT) has been recommended, but there are not enough data about its validity and accuracy, particularly in women. The aim of this study ...

journal_title：Medicina clinica

authors： Pérula de Torres LA,Fernández-García JA,Arias-Vega R,Muriel-Palomino M,Márquez-Rebollo E,Ruiz-Moral R

更新日期：2005-10-08 00:00:00

abstract：:Usher syndrome includes hereditary pathologies characterized by bilateral sensorineural deafness and visual impairment due to retinitis pigmentosa. Clinically, there are three distinct subtypes referred to as USH1, USH2, and USH3. Each subtype is genetically heterogeneous. Eleven different genes are implicated in the ...

journal_title：Medicina clinica

authors： Nájera C,Beneyto M,Millán JM

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Although impaired diastolic function is frequently found in systemic hypertension, the diagnosis of hypertensive heart disease (HHD) is based on the demonstration of left ventricular (LV) growth. The aim of the current work was to investigate the potential interactions between diastolic functio...

journal_title：Medicina clinica

authors： Martín Raymondi D,Díaz Dorronsoro I,Barba J,Díez J

更新日期：2005-09-17 00:00:00